ABSTRACT
Digital medicine underwent the conversion from "digital human" to digital medical technology and has been widely used in all aspects of clinical medicine in recent 10 years,especially in hilar cholangiocarcinoma (HCCA).It is difficult to accurately evaluate the longitudinal and vertical tumor invasion by preoperative conventional imaging assessment (CT,MRI,etc.) due to the complexity of this operation.Three-dimensional (3D) visualization can see more comprehensively,more clearly and more accurately on the basis of organs and lesions indicated by CT and MRI.Three-dimensional visualization digital medical technology can accurately,intuitively and stereoscopically display the situation of tumor invasion of the adjacent important vessels as well as the variation of vessels.It plays an important role in the aspects of preoperative evaluation,surgical planning,improving the success rate of operation and reducing complications for HCCA.It also transforms the past model of "crossing the river by feeling the stone" to now "crossing the river by watching the stone".Therefore,it is known as the paradigm of translational medicine.
ABSTRACT
Retinal macrophages and (or) microglial cells play important roles in regulating inflammation,angiogenesis and tissue repairing,thus affect the development and prognosis of ischemic retinal disease,ocular immune diseases and ocular tumors.Reversing the polarization imbalance of these cells may provide new therapeutic strategies for ischemic retinal disease and ocular immune diseases.The duality of the polarization direction of these cells is still controversial in the inflammatory reaction and pathological angiogenesis of ischemic retinal disease.Meanwhile,the plasticity and diversity of the function need to be further studied and discussed.
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With the research progress of pathogenesis of JAK gene in myeloproliferative neoplasms (MPN), more tyrosine kinase inhibitors were developed. MPN quantify scoring system is used to determine the efficacy of tyrosine kinase inhibitors for MPN. The choice of tyrosine kinase inhibitors, tyrosine kinase for the relief of MPN symptom burden, etc, become the topics of the 57th American Society of Hematology (ASH) annual meeting.
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Objective: To compare moxibustion sensation and infrared thermography by the assessment of heat-sensitization on Guanyuan (CV 4) in patients with primary dysmenorrhea, and to prove the possibility of adopting infrared thermography as an objective demonstration of acupoints heat-sensitization. Methods: Seventy-one patients with primary dysmenorrhea were enrolled to receive moxibustion and infrared to detect the heat-sensitization of Guanyuan (CV 4). The results were then analyzed and compared. Results: The infrared radiation showed a lower temperature when the acupoint Guanyuan (CV 4) was sensitized in patients with primary dysmenorrhea. Compared with moxibustion sensation, its sensitivity rate (real positive rate) was 76.6%, divergence rate (real negative rate) was 70.1%, and the accuracy rate was 74.6%. After giving moxibustion to Guanyuan (CV 4), the infrared radiation area was significantly expanded longitudinally and transversely. Compared with moxibustion test, the sensitivity rate (real positive rate) of infrared test was 78.7%, divergence rate (real negative rate) was 83.3%, and the accuracy rate was 80.3%. Conclusion: To a certain extent, the heat-sensitization of the acupoint Guanyuan (CV 4) in patients with primary dysmenorrhea can be revealed by infrared thermography. The acupoint heat-sensitization phenomena (heat extension or transmission) after giving moxibustion to the heat-sensitized acupoints can also be demonstratedobjectively by infrared thermography, besides experienced subjectively by the receivers.
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0.05), while clinical control rate of the treatment group was better than the control group (P